Belladonna
Belladonna is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| belladonna alkaloids with phenobartbital | unapproved drug other | 2013-08-21 |
| belladonna and opium | unapproved drug other | 2024-01-11 |
| contac gold | OTC monograph final | 2019-03-18 |
| migraine pack | ANDA | 2017-01-13 |
| phenobarbital with belladonna alkaloids | unapproved drug other | 2020-08-05 |
| re-pb hyos elixir | unapproved drug other | 2011-01-26 |
Indications
FDA
EMA
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Agency Specific
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Patent Expiration
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ATC Codes
A: Alimentary tract and metabolism drugs
— A03: Drugs for functional gastrointestinal disorders
— A03B: Belladonna and derivatives containing drugs, plain for functional gastrointestinal disorders
— A03BA: Belladonna alkaloids, tertiary amines for functional gastrointestinal disorders
— A03BA04: Belladonna total alkaloids
— A03BB: Belladonna alkaloids, semisynthetic, quaternary ammonium compounds for functional gastrointestinal disorders
— A03C: Antispasmodics in combination with psycholeptics
— A03CB: Belladonna and derivatives in combination with psycholeptics
— A03CB02: Belladonna total alkaloids and psycholeptics
— A03D: Antispasmodics in combination with analgesics
— A03DB: Belladonna and derivatives in combination with analgesics
— A06: Drugs for constipation
— A06A: Drugs for constipation
— A06AB: Contact laxatives
— A06AB30: Contact laxatives in combination with belladonna alkaloids
HCPCS
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Clinical
Clinical Trials
309 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 3 | 7 | 13 | 16 | 15 | 54 |
| Myopia | D009216 | EFO_0003927 | H52.1 | 7 | 7 | 8 | 6 | 13 | 39 |
| Asthma | D001249 | EFO_0000270 | J45 | 1 | 2 | 2 | 9 | 5 | 19 |
| Neuromuscular blockade | D019148 | — | — | 1 | 3 | 2 | 6 | — | 11 |
| Bradycardia | D001919 | — | R00.1 | — | 1 | — | 6 | 3 | 10 |
| Amblyopia | D000550 | — | H53.00 | — | — | 7 | 1 | 1 | 9 |
| Healthy volunteers/patients | — | — | — | 5 | — | — | 1 | 2 | 8 |
| Nausea | D009325 | — | R11.0 | — | — | — | 3 | 4 | 7 |
| Vomiting | D014839 | — | R11.1 | — | — | — | 3 | 3 | 6 |
| Spinal anesthesia | D000775 | — | — | — | — | — | 4 | 2 | 6 |
Show 65 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Motion sickness | D009041 | — | T75.3 | 1 | 4 | 7 | — | — | 10 |
| Lung diseases | D008171 | EFO_0003818 | J98.4 | — | 1 | 3 | — | 4 | 8 |
| Obstructive lung diseases | D008173 | — | — | — | 2 | 1 | — | 4 | 7 |
| General anesthesia | D000768 | — | — | — | 2 | 2 | — | 2 | 6 |
| Anesthesia | D000758 | — | — | — | — | 2 | — | 4 | 6 |
| Organophosphate poisoning | D062025 | — | — | 1 | 2 | 2 | — | — | 4 |
| Premedication | D011292 | — | — | — | 2 | 2 | — | — | 2 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | 1 | — | — | 2 |
| Hypospadias | D007021 | EFO_0004209 | Q54 | — | 1 | 1 | — | — | 1 |
| Cerebral infarction | D002544 | — | I63 | — | 1 | 1 | — | — | 1 |
Show 11 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sialorrhea | D012798 | — | K11.7 | 1 | 3 | — | — | 2 | 5 |
| Degenerative myopia | D047728 | — | H44.2 | 2 | 2 | — | — | 1 | 4 |
| Heart arrest | D006323 | EFO_0009492 | I46 | — | 1 | — | — | 1 | 2 |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | 2 | — | — | — | 2 |
| Space motion sickness | D018489 | EFO_1001188 | — | — | 2 | — | — | — | 2 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | 1 | — | — | — | 1 |
| Hemostatic disorders | D020141 | — | — | — | 1 | — | — | — | 1 |
| Heart valve diseases | D006349 | EFO_0009551 | I08 | — | 1 | — | — | — | 1 |
| Treatment-resistant schizophrenia | D000090663 | — | — | 1 | 1 | — | — | — | 1 |
| Amyotrophic lateral sclerosis | D000690 | EFO_0000253 | G12.21 | — | 1 | — | — | — | 1 |
Show 12 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | 2 | — | — | — | 1 | 3 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | 1 | — | — | — | 1 | 2 |
| Hypoglycemia | D007003 | — | E16.2 | 2 | — | — | — | — | 2 |
| Memory disorders | D008569 | — | — | 2 | — | — | — | — | 2 |
| Pulmonary atelectasis | D001261 | — | J98.1 | 1 | — | — | — | 1 | 2 |
| Dementia | D003704 | EFO_0003862 | F03 | 2 | — | — | — | — | 2 |
| Status asthmaticus | D013224 | — | — | 1 | — | — | — | — | 1 |
| Glucose intolerance | D018149 | HP_0000833 | R73.03 | 1 | — | — | — | — | 1 |
| Digestive system physiological phenomena | D004068 | — | — | 1 | — | — | — | — | 1 |
| Gastrointestinal motility | D005769 | — | — | 1 | — | — | — | — | 1 |
Show 15 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inhalation anesthesia | D000769 | — | — | — | — | — | — | 2 | 2 |
| Acute kidney injury | D058186 | — | N17 | — | — | — | — | 1 | 1 |
| Rhytidoplasty | D015361 | — | — | — | — | — | — | 1 | 1 |
| Blood coagulation tests | D001780 | — | — | — | — | — | — | 1 | 1 |
| Postoperative cognitive complications | D000079690 | — | — | — | — | — | — | 1 | 1 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | — | — | — | — | 1 | 1 |
| Urinary bladder neoplasms | D001749 | — | C67 | — | — | — | — | 1 | 1 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | — | — | 1 | 1 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | — | — | — | 1 | 1 |
| Sudden death cardiac | D016757 | EFO_0004278 | — | — | — | — | — | 1 | 1 |
Show 32 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Belladonna |
| INN | — |
| Description | Belladonna or Bella Donna may refer to:
|
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108906 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
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Variants
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Financial
Revenue by drug
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Estimated US medical usage
Belladonna
+
Butabarbital
+
Atropa belladonna
Total medical expenditures per year (USD, in millions)
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Belladonna
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Ergotamine
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Phenobarbital
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Atropa belladonna
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Trends
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Safety
Black-box Warning
Black-box warning for: Belladonna alkaloids with phenobartbital, Belladonna and opium
Adverse Events
Top Adverse Reactions
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871 adverse events reported
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